Solvent‐Free Iodination of Arenes using Iodine–Silver Nitrate Combination

Abstract

A simple and environmentally safe general method of iodination of aromatic substrates under sovent‐free conditions using the I₂/AgNO₃ combination in a solid state is reported. Both activated and deactivated aromatic compounds afford the respective aryl iodides in generally high yields (80–90%).

Keywords:

• aryl iodides
• iodination
• iodine
• silver nitrate

Acknowledgments

The authors thank Victor D. Filimonov (Department of Organic Chemistry, Tomsk Polytechnic University) for helpful discussion. V. V. Z. is thankful to the National Science Foundation (NSF/CHE‐0353541 and NSF‐MRI award CHE 0416157) for partial support of this research.