Abstract
A protocol for the direct cross coupling of trialkylsilyl‐alkynes bearing electron‐withdrawing groups and aryl halides using a Pd/Ag catalytic system is described. The procedure allows the straightforward synthesis of a variety of alkynylphosphonates and aryl propiolates derivatives in good yields.
Acknowledgment
This work was supported by the Nuclear Toxicology program of the CEA, for which grateful acknowledgment is made. We also thank E. Zekri and D. Buisson for experimental assistance with MS and LC/MS measurements.