Rapid and Efficient Method for the Synthesis of Acylals from Aldehydes and Their Deprotection Catalyzed by p‐Toluene Sulphonic Acid (p‐TSA)

Abstract

A simple, rapid, and efficient method has been developed for the synthesis of acylals from aldehydes using acetic anhydride in the presence of a catalytic amount p‐TSA at 25°C, and the deprotection of acylals using water and catalytic p‐TSA under microwave irradiation has been achieved in excellent yields.

Keywords:

• acylals
• aldehydes
• microwave irradiation
• p‐TSA
• solvent‐free condition