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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 37, 2007 - Issue 12
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Original Articles

Synthesis of Biologically Active Carvacrol Compounds using Different Solvents and Supports

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Pages 1957-1964 | Received 27 Oct 2006, Published online: 22 Jun 2007
 

Abstract

Natural monoterpenoids have been documented for their acute toxicity and repellent, antifeedent, reproduction inhibitory, and insecticidal actions. The present work aims to derive a variety of ether and ester compounds using polymer‐supported reactions from the polymer‐supported carvacrol anion was reacted with alkyl halides and acid chlorides to afford carvacryl ethers and esters, respectively. Furthermore, a special study on the effect of different solvents and supports revealed that Amberlite IRA 400 (chloride form) was found to be the best polymer support and acetone among the solvents.

Acknowledgment

U. B. More and H. P. Narkhede are thankful to University Grants Commission (UGC), New Delhi, for providing a teacher fellowship under the Faculty Improvement Programme (FIP) the Scheme of Xth UGC Plan. This paper was first presented at the Joint International Conference: Advances in Organic Chemistry and Chemical Biology, IICT, Hyderabad, Jan. 11–12, 2006. It is dedicated to Prof. R. K. Padalkar, Balwant College, Vita (Dist. Sangli), on his 60th birthday.

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