SO₄²⁻/SnO₂: Efficient, Chemoselective, and Reusable Catalyst for Acylation of Alcohols, Phenols, and Amines at Room Temperature

Abstract

SO₄ ²⁻/SnO₂ was employed for the acylation of a variety of alcohols, phenols, and amines under solvent‐free conditions at room temperature. This method showed preferential selectivity for acetylation of the amino group in the presence of a hydroxyl group. The reported method is simple, mild, and environmentally viable, using several other acid anhydrides at room temperature.

Keywords:

• acetylation, acylation, chemoselective, room temperature

Acknowledgments

The authors are thankful to Regional Sophisticated Instrumental‐analysis Centre (RSIC), Indian Institute of Technology, Mumbai, for providing the ¹H NMR facility.