Abstract
A facile and convenient method for the direct preparation of methyl 2,3,6‐tri‐O‐benzyl‐α‐D‐glucopyranoside (2) by the regioselective benzylation of methyl α‐D‐glucopyranoside (1) with benzyl bromide in the presence of mild bases K2CO3 and KOH (1∶1) without solvents is reported.
Acknowledgment
The financial support from the National Natural Science Foundation of China (20472015), the Program of Science and Technology (S&T) of Hebei (3276414), the Natural Science Foundation of Hebei (2005000106), and the Open Research Fund Program of Key Laboratory of Marine Drugs of Ministry of Education of China (KLMD[OUC]200407) are gratefully acknowledged.