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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 37, 2007 - Issue 13
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Original Articles

Knoevenagel Condensation of Aromatic Aldehydes with Active Methylene Compounds using a Catalytic Amount of Iodine and K2CO3 at Room Temperature

Yi‐Ming Ren Chemical Engineering College, Nanjing University of Science and Technology, Nanjing, China
&
Chun Cai Chemical Engineering College, Nanjing University of Science and Technology, Nanjing, ChinaCorrespondence[email protected]
Pages 2209-2213 | Received 27 Sep 2006, Published online: 03 Jul 2007
 
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Abstract

A convenient method for Knoevenagel condensation of aromatic aldehydes with malononitrile or ethyl cyanoacetate has been developed using the inexpensive and environmentally friendly reagent I2/K2CO3 at room temperature. The method is mild and simple with good to high product yields.

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