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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 37, 2007 - Issue 23
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Original Articles

Ring‐Opening of Benzocyclobutenol with Mild Bases and Trapping with Dieneophiles

Pages 4183-4189 | Received 09 May 2007, Published online: 10 Dec 2007
 

Abstract

The treatment of benzocyclobutenol with a mild base has been investigated. This reaction results in an electrocyclic opening of the cyclobutene to the corresponding o‐quinodimethane, which has been successfully treated with aldehydes and electron‐deficient alkenes to form benzolactols and benzocyclohexenes respectively.

Acknowledgments

Yong Li is thanked for useful suggestions.

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