Abstract
A new application of NBS, which results in the oxidative coupling of β‐keto esters to selectively form C‐C single and C˭C double bonds, can be controlled by the amount of NBS and t‐BuOK employed. This methodology adds a new entry to C‐C single and C˭C double‐bond formation between active methylene groups under mild conditions with high selectivity.
Acknowledgment
This work was supported by Central China Normal University, the Scientific Research Foundation for the Returned Overseas Chinese Scholars, and State Education Ministry (No. [2005] 383).