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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 38, 2008 - Issue 2
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Original Articles

Efficient DMF‐Promoted Solventless Hydrolysis of Epoxides with Equimolar Amount of H2O, Affording 1,2‐Diols

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Pages 232-238 | Received 20 Jun 2007, Published online: 18 Jan 2008
 

Abstract

A mild and efficient N,N‐dimethylformamide (DMF)–catalyzed solvent‐free hydrolysis of epoxides with an equimolar amount of H2O to afford 1,2‐diols in good to excellent yields has been developed.

Acknowledgments

This project was supported by the National Natural Science Foundation of China (20573061) and the Specialized Research Fund for the Doctoral Program of Higher Education (20060003079).

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