Isocyanide‐Catalyzed Reaction of Tetracyanoethylene and Activated 1,3‐Dicarbonyl CH‐Acid Compounds: A Rapid and Efficient Synthesis of Pyran Annulated Heterocyclic Systems

Abstract

An isocyanide‐catalyzed reaction between tetracyanoethylene and various activated CH‐acid compounds to afford the corresponding pyran annulated heterocyclic ring systems, in high yield at room temperature within a few minutes, is described. To the best of our knowledge, this is the first example in which isocyanide functions as only a catalyst but not a reagent.

Keywords:

• CH‐acid
• isocyanide‐catalyzed reaction
• pyrans
• tetracyanoethylene

Acknowledgment

We gratefully acknowledge the financial support from the Research Council of Shahid Beheshti University.