(NH₄)₃PW₁₂O₄₀ as an Efficient and Reusable Catalyst for the Synthesis and Deprotection of 1,1‐Diacetates

Abstract

An efficient method for the synthesis of 1,1‐diacetates (acylals) from different aldehydes in the presence of (NH₄)₃PW₁₂O₄₀ and acetic anhydride under solvent‐free conditions at ambient temperature is achieved. Selective conversion of aldehydes was observed in the presence of ketones. The deprotection of acylals has also been achieved using (NH₄)₃PW₁₂O₄₀ in methanol. The catalyst was found to possess good activity and considerable level of reusability.

Keywords:

• 1,1‐diacetates
• (NH₄)₃PW₁₂O₄₀
• protection and deprotection
• room temperature

Acknowledgment

The authors are thankful to RSIC, Indian Institute of Technology Mumbai, for providing the ¹H NMR facility.