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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 38, 2008 - Issue 5
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Original Articles

Sulfamic Acid as a Novel, Efficient, Cost‐Effective, and Reusable Solid Acid Catalyst for the Synthesis of Pyrroles under Solvent‐Free Conditions

Pages 803-809 | Received 13 Sep 2007, Published online: 15 Feb 2008
 

Abstract

Paal–Knorr condensation of 2,5‐hexadione with primary amines in the presence of a catalytic amount of sulfamic acid under solvent‐free conditions has been accomplished with an excellent yield. This is a very easy, rapid, and high‐yielding reaction for the synthesis N‐substituted pyrrole derivatives.

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