Novel Synthesis and Characterization of N‐Substituted‐calix[4]azacrown Derivatives

Abstract

Novel calix[4]azacrown derivatives from the reaction between calix[4]amidocrown and the different N‐(4‐bromoacetamidephthalimido)alkanes derivatives, which may be useful intemediate compounds of pseudorotaxane, have been synthesized and structurally characterized by IR, ¹H NMR, ¹³C NMR, MS, and elemental analyses. From their analysis data, it was found that compounds 6a–d adopted a cone conformation.

Keywords:

• calix[4]azacrown
• characterization
• conformation
• n‐(4‐bromoacetamidephthalimido)alkanes
• synthesis

Acknowledgments

The support of the National Natural Science Foundation of China (No. 20376059) and Natural Science Foundation of Tianjin (No. 07JCZDJC00300) is acknowledged.