Facile Synthesis of 2‐Amino‐1,4‐naphthoquinones catalyzed by Molecular Iodine under Ultrasonic Irradiation

Abstract

The conjugate addition reactions of amines with 1,4‐naphthoquinone were catalyzed efficiently by molecular iodine under ultrasonic irradiation to afford 2‐amino‐1,4‐naphthoquinones in moderate to excellent yields.

Keywords:

• 2‐Amino‐1,4‐naphthoquinones
• molecular iodine
• ultrasound

Acknowledgments

The work was supported by the National Natural Science Foundation of China (Nos. 20472062 and 20672079), the Natural Science Foundation of Jiangsu Province (Nos. BK2004038 and BK2006048), the Key Laboratory of Organic Synthesis of Jiangsu Province (No. S8109108), Nature Science Key Basic Research of Jiangsu Province for Higher Education (Nos. 06KJA15007 and 05KJB150116), the Key Laboratory of Fine Petroleum Chemistry of Jiangsu Province (No. KF0402), and a research grant from the Innovation Project for Graduate Students of Jiangsu Province.