Abstract
A series of 3-(N-hydroxylamino)-1,3-diarylpropan-1-one oximes have been synthesized through the reaction of chalcones and hydroxylamine hydrochloride in 56–96% yield within 2–3 h in the presence of sodium acetate in EtOH under ultrasound irradiation.
ACKNOWLEDGMENTS
We thank the Natural Science Foundation of Hebei Province (B2006000969), China, for financial support.
Notes
a Reaction temperature: 36–40°C, substrate: PhCOCH = CHPh: 2 mmol; amount of NaAc: 0.492 g.
b Stirred without ultrasound irradiation.