Abstract
A series of weakly nucleophilic nitrogen derivatives including carbamates, amides, sulfonamides, and anilines were reacted with 1,2‐bis(trimethylsilyloxy)cyclobutene under acidic conditions to afford various substituted 2‐aminocyclobutanone derivatives 3a–i in modest to excellent yields.
Acknowledgments
NSF Grant DBI‐0216630 is gratefully acknowledged for the Varian Unity‐300 NMR obtained through the NSF Biological Major Instrumentation Program, and the NSF REU Program (Research Experience for Undergraduates) is gratefully acknowledged for summer financial support for N. A.