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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 38, 2008 - Issue 11
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Original Articles

Convenient Synthesis of Structurally Novel 1,3‐Disubstituted Azetidine DerivativesFootnote

, , , , &
Pages 1703-1717 | Received 30 Aug 2007, Published online: 09 May 2008
 

Abstract

A convenient synthesis of structurally novel 1,3‐disubstituted azetidine derivatives is described. The approach involves condensation of an azetidine building block with sulfonylated carbamic acid methyl ester, subsequently followed by quenching the imidoyl chloride with amines. Different derivatives were prepared by substituting benzhydrol as well as benzenesulfonamide as part of the core structure.

Acknowledgment

We thank the management of Zydus Group for encouragement and our analytical department for support.

Notes

ZRC Communication No. 182

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