Abstract
1,5-Benzodizepines are synthesized in excellent yields via condensation of o-phenylenediamine with ketones having a hydrogen at the α-position. The reaction is performed in solvent-free conditions and 5 mol% of RuCl3·xH2O is enough to direct the reaction to completion.
ACKNOWLEDGMENT
The authors are thankful to the Council of Scientific and Industrial Research, New Delhi, India, for financial assistance and to the Indian National Science Academy, New Delhi, India, for additional financial support for this research project.
Notes
a All the products were characterized by comparison of their spectral and physical data with those of authentic samples
b Isolated yields
c Using 5 mol% of RuCl3·xH2O
d Using 2mol% of RuCl3·xH2O
e Using 10 mol% of RuCl3·xH2O