Abstract
The microwave-enhanced reactions of 4-amino-5-mercapto-3-substituent-1,2,4-triazoles with benzoyl chloride or arylaldehydes under solvent-free conditions without catalyst were studied. 3-Substituded-6-phenyl-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles were easily prepared by the reactions of 4-amino-5-merecapto-3-substituded-1,2,4-triazoles with benzoyl chloride. 4-Arylideneamino-5-mercapto-3-substituted-1,2,4-triazoles were obtained by the condensation of 4-amino-5-mercapto-3-substituent-1,2,4-triazoles with arylaldehydes. This method possessed such advantages as short reaction time, environmentally benign procedures, easy purification, and high yield.
ACKNOWLEDGMENTS
We gratefully acknowledge the Special Foundation of the Education Committee of Shaanxi Province (No. 07JK378) for support of this work.