Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 38, 2008 - Issue 19
244
Views
43
CrossRef citations to date
0
Altmetric
Original Articles

PPA-SiO2–Catalyzed Multicomponent Synthesis of Amidoalkyl Naphthols

, &
Pages 3375-3389 | Received 21 Feb 2008, Published online: 12 Sep 2008
 

Abstract

Silica gel–supported polyphosphoric acid (PPA-SiO2) was found to be an efficient catalyst for the multicomponent condensation reaction of aryl aldehydes, 2-naphthol, and urea or amides to afford the corresponding 1-amidoalkyl-2-naphthols in good to excellent yields. This new approach consistently had short reaction times, high conversions, clean reaction profiles, and simple experimental and workup procedures.

ACKNOWLEDGMENTS

We are thankful to the Sistan and Baluchestan University Research Council for the partial support of this research.

Notes

a Yield refers to the isolates pure products.

a Yield refers to the isolated pure products. All known products have been reported previously in the literature and were characterized by comparison of IR and NMR spectra with authentic samples.[ Citation6-15 ]

b Yield after recovery of catalyst five times.

a Based on 2-naphthol (1 equiv.), benzaldehyde (1 equiv.) and acetamide (1.2 equiv.).

Log in via your institution

Log in to Taylor & Francis Online

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 61.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 422.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.