Vanadyl(IV) Acetate: An Efficient, Reusable Heterogenous Catalyst for Aza-Michael Reaction Under Solvent-Free Conditions

Abstract

Vanadyl(IV) acetate [VO(OAc)₂] efficiently catalyzes the conjugate addition of aliphatic, aromatic amines to α,β-unsaturated carbonyl compounds in solvent-free media at room temperature to afford corresponding amino compounds in good to excellent yields. The catalyst can be recovered and reused for further cycles.

Keywords:

• Amines
• aza-Michael reaction
• solvent free
• vanadyl(IV) acetate

ACKNOWLEDGMENT

We thank CSIR for the research funding.

Notes

^a Reaction conditions: olefin (1.2 mmol), amine (1 mmol), catalyst (5 mol%), solvent (2 mL), and room temperature.

^b Isolated yields.

^a Reaction conditions: olefin (1.2 mmol), amine (1 mmol), catalyst (5 mol%), room temperature.

^b Yield after 5th cycle.