γ-Al₂O₃-Supported 12-Tungstosilicic Acid as an Efficient Heterogeneous Catalyst for the Synthesis of α-Aminonitrile

Abstract

The multicomponent Strecker reaction using trimethylsilyle cyanide was performed in very short reaction times, and α-aminonitriles were prepared in excellent yields in the presence of a catalytic amount of alumina-supported tungstosilicic acid.

Keywords:

• Alumina
• α-aminonitrile
• heterogeneous catalyst
• strecker reaction
• supported heteropoly acid

ACKNOWLEDGMENT

The authors thank the Razi University Research Council and Kermanshah Oil Refining Company for support of this work.

Notes

^a Isolated yield.

^a Isolated yield

^b Products were characterized by comparison of their spectroscopic data with those reported in the literature.