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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 39, 2008 - Issue 2
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Original Articles

TiO2-Mediated, One-Pot, Four-Component 1,3-Dipolar Cycloaddition Reaction: A Facile Synthesis of Dispiro-pyrrolidine Ring Systems

A. R. Suresh Babu Department of Organic Chemistry, University of Madras, Guindy Campus, Guindy, Chennai, India
&
R. Raghunathan Department of Organic Chemistry, University of Madras, Guindy Campus, Guindy, Chennai, IndiaCorrespondence[email protected]
Pages 347-354 | Received 12 Apr 2008, Published online: 22 Dec 2008
 
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Abstract

An expedient regioselective synthesis of dispiroindenoquinoxaline pyrrolidine derivatives mediated by TiO2 in a one-pot, four-component 1,3-dipolar cycloaddition reaction is described.

ACKNOWLEDGMENTS

A. R. S. thanks the Council of Scientific and Industrial Research (CSIR), New Delhi, for the award of a senior research fellowship. R. R. thanks Department of Science and Technology (DST) and DST-Fund for Improvement S-T (FIST) for financial assistance.

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