Microwave-Assisted Syntheses of 2-Phenylbenzothiazoles

Abstract

A new and easy synthetic route to 2-phenylbenzothiazoles has been achieved by direct thiation of benzoyl derivatives of aniline, various substituted anilines, and 1-naphthylamine under microwave irradiation. The oxidative cyclization using elemental sulfur in the presence of a catalytic amount of iodine is inexpensive and worked well for a number of anilides.

Keywords:

• Anilides
• benzothiazoles
• microwave
• oxidative cyclization
• thiation

ACKNOWLEDGMENTS

The authors acknowledge the financial assistance of UGC in the form of minor research project. The help of Prof. A. Sarkar, Prof. D. Mal, Bimalendu Roy, Dr. Subrata K. Pal, and Kaushik Chandra in collecting spectra of products and of Dr. Kumaresh Ghosh for discussions in the course of the work is thankfully acknowledged.

Notes

^a All the products have been characterized by ^IH NMR, ¹³C NMR, IR and mass spectral studies.