Montmorillonite K10–Catalyzed Michael Addition of Indoles to Nitroolefins Under Solvent-Free Conditions

Abstract

Montmorillonite K10 is a very inexpensive and readily available reagent and efficiently catalyzes the Michael addition of indoles to nitroolefins under solvent-free conditions. Reasonable to excellent yields of the desired products were obtained in most cases.

Keywords:

• Indole
• Michael addition
• montmorillonite K10
• nitroolefin
• solvent-free

ACKNOWLEDGMENT

We thank Suzhou University for financial support.

Notes

^a Reaction conditions: indole (0.2 mmol), β-nitrostyrene (0.21 mmol), and montmorillonite K10 (20 mg).

^b Isolated yield.

^a Reaction conditions: indole (0.2 mmol), nitroolefin (0.21 mmol), and montmorillonite K10 (20 mg).

^b Isolated yield.