NbCl₅ as an Efficient Catalyst for Chemoselective Synthesis of 1,1-Diacetates Under Solvent-Free Conditions

Abstract

A mild and efficient method for the chemoselective preparation of 1,1-diacetates catalyzed by NbCl₅(5 mmol%) under solvent-free conditions has been developed. The yields are in the range of 93–98%. This protocol offered several advantages, including low catalyst loading, good yields, short reaction times, and environmentally friendliness.

Keywords:

• Aldehydes
• 1,1-diacetates
• NbCl₅
• solvent-free conditions

ACKNOWLEDGMENTS

This work was financially supported by the Natural Science Foundation of the Agricultural University of Hebei.