Triton B–Mediated Mild, Convenient, and Efficient Method for the Selective Alkylation of Cyclic Secondary Amines and Thiols

Abstract

Alkylation of cyclic secondary amines, thiols, and pyridazinones has been demonstrated with alkyl halides using Triton B as base and reaction medium.

Keywords:

• Alkyl halides
• amines
• thiols
• Triton B

ACKNOWLEDGMENTS

B. C. K. R. and P. R. G. thank the Council of Scientific and Industrial Research–University Grants Commission for the award of a fellowship and Dr. J. S. Yadav, director, Indian Institute of Chemical Technology, for his support and encouragement.

Notes

^a All the products exhibited physical and spectral (NMR, mass, IR) properties in accordance with the assigned structure.

^b All reactions are carried out at rt only.

^c Isolated yield.