A Simple and Convenient One-Pot Synthesis of Benzimidazole Derivatives Using Cobalt(II) Chloride Hexahydrate as Catalyst

Abstract

A simple and efficient method for the convenient synthesis of 2-arylbenzimidazole has been described on reaction with o-phenylenediamine and various aromatic aldehydes using cobalt(II) chloride hexahydrate as a catalyst. The method is cost-effective, high-yielding, clean, and selective.

Keywords:

• Aldehydes
• benzimidazole
• catalysis
• cobalt(II) chloride hexahydrate
• o-phenylene diamine

ACKNOWLEDGMENTS

T. P. is thankful to the Indian Institute of Technology Guwahati (IITG) for her research fellowship. Authors are also grateful to the director, IITG, for providing the general facilities to carry out the work.

Notes

^a Products were characterized by recording IR, ¹H NMR, and ¹³C NMR spectra and elemental analysis.

^b Isolated yield.