Abstract
An efficient method has been successfully developed for the synthesis of oxygen-bridged pyrimidine tricyclic derivatives from salicylaldehyde, ethyl acetoacete, and urea catalyzed by PdO in very good yield. A series of different oxygen-bridged pyrimidine tricyclic derivatives has been synthesized, in which two compounds’ x-ray crystal structure were obtained.
ACKNOWLEDGMENTS
This research was supported by the National Natural Science Foundation of China (20572091, 20576111) and the Cultivation and Construction Fund for the State Key Subject of Physical Chemistry. We thank the Testing Center of Yangzhou University for characterizing our compounds. We gratefully acknowledge Dr. Jun Ye for help with crystal refinement.