H₃Mo₁₂O₄₀P-Catalyzed One-Pot Synthesis of Amidoalkyl Naphthols

Abstract

Solid H₃Mo₁₂O₄₀P is used for an efficient one-pot synthesis of amidoalkyl naphthols using aromatic aldehydes, β-naphthol, and urea or amides in carbon tetrachloride. The catalyst was efficiently recovered from the reaction mixture and reused with negligible loss of catalyst activity. Ambient conditions, simple workup, and good yield are some of the striking features of the present protocol.

Keywords:

• Amidoalkyl naphthols
• aryl aldehyde
• β-naphthol
• one-pot reaction
• phosphomolybdic acid
• urea or amides

ACKNOWLEDGMENTS

We gratefully acknowledge the financial support from the University Grants Commission, New Delhi, and the University of Mumbai. We thank Dr. S. T. Gadade, principal, C. K. Thakur College, for providing all the facilities.