Abstract
An efficient, mechanically activated solid-state synthesis of flavones from 1-(2-hydroxyphenyl)-3-aryl-1,3-propanediones using high-speed ball milling is described. This method has notable advantages in terms of good yield, short reaction time, and neat conditions.
ACKNOWLEDGMENT
We are grateful to the Natural Science Foundation of China (Nos. 20476098 and 20876147) for financial help.
Notes
a Reactions were run with 10 mmol of 1-(2-hydroxyphenyl)-3-phenyl-1,3-propanedione, catalyst and 10 g silica gel.
b Isolated yield.
a Reactions were run with 10 mmol of substrate, 1 mmol of KHSO4, and 10 g silica gel.
b Isolated yield.
a Reactions were run with 10 mmol of substrate, 1 mmol of KHSO4, and 10 g silica gel.
b Isolated yield.