Efficient One-Pot Suzuki–Miyaura Double Cross-Coupling Reactions Using Very Low Pd(PPh₃)₄ Catalyst Loading

Abstract

Suzuki–Miyaura double cross-coupling to form teraryls of interest as Schiff-base precursors can be achieved efficiently in near-quantitative yields using a low mol% amount of Pd(PPh₃)₄ and easily accessible dibromoaryls.

Keywords:

• Dibromoaryls
• palladium-catalyzed cross-coupling
• Suzuki–Miyaura
• teraryls

ACKNOWLEDGMENTS

This work was supported by Memorial University of Newfoundland and National Sciences and Engineering Research Council of Canada (NSERC). Prof. G. Bodwell is thanked for his insightful comments.

Notes

^a Yields reported are based upon isolated yields. Experimental details are included in the Experimental section.

^a Yields reported are based upon isolated yields. Compounds other than those reported in the Experimental section are based upon comparisons with those same compounds reported in the literature.