Abstract
Solvent-free acetylation of alcohols, phenols, amines, and thiols with acetic anhydride (Ac2O) in the presence of 0.1 mol% (13 mg) anhydrous NiCl2, an inexpensive and easily available catalyst, is described. Excellent yields, short reaction time, and mild reaction conditions are important features of this method.
ACKNOWLEDGMENT
The authors acknowledge the partial support of this work by Prof. B. P. Bandgar, Vice Chancellor, University of Solapur, India.
Notes
a Yields refer to pure products, and all products were characterized by comparison of their IR data, 1H NMR spectrum, and elemental analysis with those of authentic samples.