Mg(NTf₂)₂·xH₂O: An Efficient Catalyst for the Synthesis of Homoallylic Alcohols in Water

Abstract

An efficient method has been developed for the allylation of aldehydes with allytributylstannane in the presence of a catalytic amount of Mg(NTf₂)₂·xH₂O at room temperature in water to afford the corresponding homoallylic alcohols in good yields.

Keywords:

• Aldehydes
• allytributylstannane
• homoallylic alcohols
• Mg(NTf₂)₂·xH₂O
• water as solvent

ACKNOWLEDGMENTS

This work was financially supported by the Educational Committee of Shaanxi Province (Nos. 08JZ09, 09JK332) and Baoji University of Arts and Sciences (No. Zk064).

Notes

^a The reaction was performed with 1 mmol of benzaldehyde and 1.2 mmol of allytributylstannane in H₂O (2 mL) at room temperature.

^b Isolated yield.

^a All the reactions were performed with 1 mol% of Mg(NTf₂)₂·xH₂O in H₂O at room temperature.

^b Isolated yield.