Chemoselective Protection of Aldehydes in the Presence of Ketones Using RuPVP Complex as a Heterogeneous Catalyst

Abstract

Ruthenium(III)-polyvinyl pyridine (RuPVP) complex was prepared by refluxing a methanolic solution of polyvinyl pyridine and trihydrated ruthenium trichloride. RuPVP catalyst was characterized by Fourier transform–infrared and diffential scanning calorimetry–thermogravimetry (TG). The catalyst was used for chemoselective protection of aldehydes in the presence of a ketonic carbonyl group.

Keywords:

• Heterogeneous catalysts
• polyvinyl pyridine
• protection

ACKNOWLEDGMENT

The authors thank the Council of Scientific and Industrial Research, New Delhi, for Research Grant No. 01 (2056)/06/EMR-II.

Notes

Note. Reaction condition: 1b (0.45 g, 3 mmol), methanol (10 ml), 4 h, at 68–70°C.

Note. Reaction condition: 1b (0.45 g, 3 mmol), alcohol (10 ml), and RuPVP (50 mg), 4 h, at 68–70°C.

Note. Reaction condition: 1b (0.45 g, 3 mmol), methanol (10 ml), and RuPVP (50 mg), 4 h, at 68–70°C.

Note. Reaction condition: Aldehyde (3 mmol), methanol (10 ml), and RuPVP (50 mg) at 68–70°C. The products were characterized by GC-MS and FT-IR.