Abstract
Two monoterpenols, perillyl alcohol and nerol, have been converted into their γ,δ-unsaturated ester derivatives following a modified process of microwave-assisted ortho ester Claisen rearrangement. The yields obtained (>90%) are better than those previously obtained. The optimized process needs less reaction time (5 min), smaller amount of reagent, and no solvent.
Notes
a Molecular ratio.
b In oil bath.
c Under microwaves.
a Molecular ratio.
b In oil bath.
c In DMF.
d Under microwaves.