Antimony Trichloride: An Efficient and Mild Catalyst for Cyclization of 2-Aminochalcones to the Corresponding 2-Aryl-2,3-Dihydroquinolin-4(1H)-ones

Abstract

Antimony trichloride is an efficient catalyst for the cyclization of 2-amino chalcones to the corresponding 2-aryl-2,3-dihydroquinolin-4(1H)-ones under mild reaction conditions and in almost quantitative yields.

Keywords:

• 2-Aminochalcones
• 2-aryl-2,3-dihydroquinolin-4(1H)-ones
• antimony trichloride
• intramolecular aza-Michael

ACKNOWLEDGMENTS

One of the authors, P. K., thanks Jadavpur University, Kolkata, and the government of West Bengal for awarding the senior research fellowship.

Notes

^a All reactions were carried out using SbCl₃ in acetonitrile at 55°C (method A).

^b All products were characterized by mp, IR, NMR, and HRMS data and are agreement with the literature values.

^c Yield refers to pure isolated products.