Brønsted Acid Ionic Liquid [(CH₂)₄SO₃HMIM][HSO₄] as Novel Catalyst for One-Pot Synthesis of Hantzsch Polyhydroquinoline Derivatives

Abstract

1-(4-Sulfonic acid)butyl-3-methylimidazolium hydrogen sulfate ([(CH₂)₄SO₃HMIM][HSO₄]) efficiently catalyzed a four-component Hantzsch reaction of aldehyde, ethylacetoacetate, dimedone, and ammonium acetate to afford the corresponding polyhydroquinoline derivatives.

Keywords:

• Brønsted acid ionic liquid
• Hantzsch reaction
• polyhydroquinoline

ACKNOWLEDGMENT

We gratefully acknowledge the partial financial support from Azzahra University.

Notes

^a Products were characterized by comparison of their spectroscopic data (GC/mass, FTIR) and mps with those reported in literature.