Abstract
Ketones are readily reduced to secondary alcohols with sodium hydroxide in refluxing isopropanol.
ACKNOWLEDGMENTS
The authors gratefully acknowledge financial support from the Covenant College Kaleo Center, an NSF RSEC grant, Research Corporation, the University of Chattanooga Foundation, and the Grote Chemistry Fund.
Notes
a Isolated yield was lowered because of the volatility of the alcohol.
b Nucleophilic aromatic substitution side products were observed in the product mixture.