Abstract
The Beckmann rearrangement of a variety of ketoximes to corresponding amides catalyzed by sulfamic acid and zinc chloride was carried out in good yields at refluxing temperature in acetonitrile.
ACKNOWLEDGMENT
The Natural Science Foundation of Hebei Province (B2006000969), China, supported the project.
Notes
a Reaction conditions: acetophenone oxime (1 mmol), sulfamic acid (0.5 mmol), Lewis acids (0.2 mmol), solvent (3 mL), reflux, 2 h.
a Acetophenone oxime: 1 mmol; acetonitrile: 3 mL; reflux.