Heteroannulated Quinazoline and Quinazolinone Derivatives from (Z)-2-[1-Benzamido-2-(3,4,5-trimethoxyphenyl)]vinyl-3,1-benzoxazin-4(3H)-one

Abstract

The title compound 1 was prepared and allowed to react with a series of nitrogen nucleophiles to afford the quinazoline and quinazolinone derivatives 2–12 and tetrazole derivative 13. The IR, ¹H NMR, ¹³C NMR, and mass spectra of all the synthesized compounds were discussed.

Keywords:

• Benzoxazin-4(3H)-one
• imidazo-[1,5-b]-quinazolin-4(3H)-one derivatives
• [1,2,5]-oxadiazino-[3,2-b]-quinazolin-4(3H)-one derivatives
• [1,2,4]-triazino-[6,1-b]-quinazolin-4(3H)-one derivatives
• [1,2,4]-triazolo-[1,5-c]-quinazolin-4(3H)-one derivatives