Abstract
A new series of 1-alkyl-2-oxo-1,2-dihydro-pyrimidine-5-carboxalic acid amides is described. The reaction of N-((E)-3-(dimethylamino)-2-formylacryloyl) formamidine, an intermediate obtained by Vilsmeier–Haack formylation of acetonitrile with various mono-substituted ureas, provides such compounds in good yields.
ACKNOWLEDGMENTS
The authors gratefully acknowledge financial support of this project by the University Grants Commission, New Delhi, India. We also thank Dr. V. B. Gaikwad for his valuable cooperation.