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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 40, 2010 - Issue 12
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Original Articles

Microwave-Induced Aza-Michael Reaction in Water: A Remarkably Simple Procedure

, &
Pages 1730-1735 | Received 16 Apr 2009, Published online: 17 May 2010
 

Abstract

Microwave-induced fast addition of several amines to conjugated carbonyl compounds has been carried out in water very efficiently in the absence of any catalyst.

ACKNOWLEDGMENT

We gratefully acknowledge the funding support from the National Institutes of Health SCORE Program (Grant 2S06M008038-37).

Notes

Note. “Ref.” indicates the corresponding literature syntheses.

a Isolated yield.

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