Accelerated Amination of Baylis–Hillman Acetates Under Ultrasound Irradiation

Abstract

The amination of the Baylis–Hillman acetates with primary amines can be dramatically promoted with improved yields and shortened reaction time under ultrasound irradiation. The selected aromatic, heteroaromatic, and aliphatic amines were investigated as the effective candidates for the sonochemical transformation.

Keywords:

• Amination
• Baylis–Hillman acetate
• primary amine
• sonication

ACKNOWLEDGMENTS

We are grateful for the financial support from the Natural Science Foundation of Zhejiang Province (Project No. R405465) and Program for Changjiang Scholars and Innovative Research Team in University (PCSIRT) (No. 0654).