Abstract
An efficient method is described for the stereoselective synthesis of diorganyl chalcogenides from a variety of Baylis–Hillman acetates and diaryl chalcogens using palladium catalyst. This reaction is a convenient new method to produce unsymmetrical sulfides and selenides in good yields.
ACKNOWLEDGMENTS
P. S. R. and M. A. R. thank the Council of Scientific and Industrial Research (CSIR), India, for the award of senior research fellowships.
Notes
Note. Reactions conditions: 1 (1 mmol), 1 (0.6 mmol), Pd catalyst (2 mol%), PPh3 (10 mol%), and solvent (3 ml) at rt for 12 h.
a Reaction conditions: Baylis–Hillman acetate (1.0 mmol), diaryl disulfide (0.6 mmol), Pd(OAc)2 (2 mol%), PPh3 (10 mol%) in methanol (3 mL) at rt.
b Products with (Z)-stereoselectivity.
c Isolated yields.
d Product with (E)-stereoselectivity.