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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 40, 2010 - Issue 22
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Original Articles

Novel Synthetic Route to Fluoxetine

Pages 3415-3422 | Received 12 Jun 2009, Published online: 15 Oct 2010
 

Abstract

Racemic fluoxetine was synthesized from 3-benzoylpropionic acid in five steps in 54% overall yield.

ACKNOWLEDGMENT

Financial support for this research was in part from the National Institute on Drug Abuse.

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