Abstract
(Carboethoxymethylene)triphenylphosphorane 1 can undergo the tandem reaction of iodination–oxidation–Wittig reaction with alcohol in the presence of N-iodosuccinimide (NIS) and manganese dioxide. The reaction constitutes a stereoselective one-pot procedure for the preparation of Z-configured α-iodo-α,β-unsaturated esters in good to excellent yield.
ACKNOWLEDGMENT
I thank the Saudi Basic Industries Corporation (SABIC) for financial support (Project Science-5–2007).
Notes
a Yields were based on alcohols.
b This ratio was determined by 1H NMR spectroscopy.