Abstract
This article describes an efficient, simple, and clean method for the synthesis of α,α′-bis(arylidene, furylidene and cinnamylidene)cycloalkanones under solvent-free conditions. The cross-aldol condensation of cycloalkanones with aldehydes in the presence of silica-supported phosphorus pentoxide (P2O5/SiO2) or silicaphosphinoxide (silphox, [POCl3-n(SiO2)n]) as heterogeneous reagents produces the title compounds in good to excellent yields.
ACKNOWLEDGMENTS
We appreciate the Persian Gulf University and Payame Noor University (PNU) Research Councils for the financial support of this work.
Notes
a Isolated yield.
a Isolated yield.
a Isolated yield.