Abstract
A simple, efficient, and practical procedure for the synthesis of imidazo[1,2-a]quinoline and quinolino[1,2-a]quinazoline derivatives using CuO nanoparticles as a novel catalyst in excellent yields is described. The catalyst can be recovered conveniently and reused at least four times without any loss of activity.
ACKNOWLEDGMENT
The authors are thankful to the Nuclear Science and Technology Research Institute for the partial financial support.
Notes
a Reaction conditions: benzaldehyde (1 mmol), malononitrile (1 mmol), and enaminone 1a (1 mmol), x mmol% catalyst; water; 50 °C.